Colisol

COMPOSITION: Time Tested Well Trusted Economical
Water Soluble Powder for Oral Use.
Each gm contains:
Colistin Sulphat e………………….. 5,000,000 I.U
MODE OF ACTION:
Colistin sho ws a strong and rapid bactericidal activity
against gram-negative bacteria, specially Salmonella
and E. Coil. It has been observed that Colistin causes
marked formal changes in the bacterial cell wall result-
ing in the discharge of cytoplasm. Colistin adheres to
the bacterial cell wall and passes into the cell mem-
brane and finally combines with phosphatide in the
bacterial cell membrane. The decrease in surface
tension destroys the membrane.
It is poorly absorbed from the Gastro-intestinal tract
after oral administration, thus offering specific advan-
tages in the treatment and control of Gastro-intestinal
infections. (Colibacillosis and Salmonellosis)
INDICATIONS:
Treatmen t of gastrointestinal infections caused by gram
nagetive bacteria in particular non-invasive Escherichia
coli susceptible t o colistin.
FEATURE:
COLISOL is suitable for a wide range of species.
COLISOL is suitable for use in drinking water.
COLISOL has potent antibacterial effect in the gut.
COLISOL exerts a potent bactericidal action on
susceptible gram negative bacteria.
COLISOL is poorly absorbed from gastro-intestinal
tract. In contrast to very low concentration of colistin in
serum and tissues, high and presistent amounts are
present with in the different sections of the gastro-in-
testinal tract.
COLISOL resistance aganist gram-negative bacteria is
rarely reported.
DOSAGE & ADMINISTRATION:
Poultry:
100 gm Colisol Powder to medicate 1000 liters of drink-
ing water.
Or 1 gm in 10 liters for 4-5 consecutive day.
Packing: Note: The medicated water should be used within 24
100gm Sachet hours.
1kg (Jar) Withdrawal period: Poultry 1 Day.